Colon Cancer

Globally, colorectal cancer also called colon cancer or bowel cancer is the third leading cause of cancer. The frequency of colorectal cancer varies around the world; it is common in the Western world and rare in Asia and Africa. In countries where people have adopted the western diets has an increasing incidence of colon cancer.

The colon also known as the large bowel is the longest portion of the large intestine. The large intestine is the last part of the digestive tract, which is a tube that is about five to six feet in length; the first five feet make up the colon which then connects to about six inches of rectum, and finally ends with the anus. About three to eight hours after eating, by the time the food reaches the colon, the nutrients have been absorbed and the remainder is liquid waste product. The colon functions as a converter, changing this liquid waste into stool. The stool can spend anywhere from ten hours to several days in the colon before being expelled through the anus. It has been advised but not proven, that the longer the stool stays in the colon, the higher the risk of colon cancer.

Colon cancer includes cancerous growths in the colon, rectum and appendix. Many colon cancers are thought to arise from adenomatous polyps in the colon. These mushroom-like growths are usually benign, but some may develop into cancer over time. This process can take years which allow time for early detection with screening tests.

Symptoms
Symptoms of colon cancer are numerous and non-specific. They include fatigue, weakness, shortness of breath, change in bowel habits, narrow stools, diarrhea or constipation, red or dark blood in stool, weight loss, abdominal pain, cramps, or bloating. Other conditions such as irritable bowel syndrome (spastic colon), ulcerative colitis, Crohn’s disease, diverticulosis, and peptic ulcer disease can have symptoms that mimic colorectal cancer. Most often, these symptoms are not due to cancer, other problems can cause the same symptoms, so checking with your doctor should be done immediately to be diagnosed and treated as early as possible.

The risk of colon cancer rises substantially after the age of fifty, but every year there are numerous cases reported in younger people. Individuals with a personal or family history of colon cancer, polyps, or inherited colon cancer syndromes (i.e., FAP and HNPCC), as well as patients with ulcerative colitis or Crohn’s disease, are all at higher risk and may require screening at an earlier age than the general population. A person with one first degree relative (parent, sibling or child) with colon cancer is two to three times as likely to develop the cancer as someone who does not have an affected relative.

The treatment depends on the staging of the cancer. When colon cancer is caught at early stages (with little spread) it can be curable. However when it is detected at later stages (when distant metastases are present) it is less likely to be curable. Surgery remains the primary treatment while chemotherapy and/or radiotherapy may be recommended depending on the individual patient’s staging and other medical factors.

Arthritis Medication

Arthritis is a painful condition of the joints that causes swelling and inflammation. It can occur at any time of a person’s life, no matter the gender. As of now, medical science has yet to find a cure to arthritis, but there are several treatment methods available to alleviate the symptoms, the most common of which is pain.

Below are some arthritis medications that have been approved for consumer use:

NSAIDs (Non Steroidal Anti Inflammatory Drugs)

NSAIDs are the most common arthritis medications, available in most drugstore shelves, supermarket, and even discount or convenient stores. As an over the counter drug, you do not need a physician’s prescription to start using this arthritis medication.

The main purpose of the drug is to reduce pain – from muscles aches and headaches to minor joint pains and fever, all of which are common symptoms of arthritis. In addition to pain reduction, NSAID can also help alleviate joint inflammation.

NSAIDs are available in three basic categories: traditional NSAIDs, COX-2 inhibitors, and salicylates.

Analgesics

Analgesics are like NSAIDs in that they can provide relief for pain. However, that is all that this arthritis medication can do. It cannot reduce inflammation or swelling of the joints. Nevertheless, analgesics are most helpful if, for some reason, the patient cannot take NSAIDs (like if he is allergic to it or suffers stomach problems if he takes that arthritis medication) to help relieve pain.

Biologic Response Modifiers

Most arthritis medications are symptom-specified. That is, they commonly target only the signs and symptoms of arthritis, such as joint pains and inflammation, not the disease itself. However, there is a class of arthritis medications that aim at halting disease progression. They are called biologic response modifiers or BRMs. This class of arthritis medication works in different ways, although all of them have something to do with a protein called cytokines. By inhibiting the production of cytokines, BRMs can effectively stop inflammation.

Corticosteroids

Corticosteroids, more commonly known as steroids, make up some of the oldest and most effective arthritis medication. It is also one of the fastest working. Joints, eyes, and internal organs that have been damaged due to arthritic inflammation can be spared with the application of steroids. Not only that, but there have been many cases where steroids saved lives.

However, this arthritis medication needs to be used properly and sparingly. Because while steroids have the potential to help arthritic patients, they also have the potential to do great harm by causing bones to become brittle, cataracts to occur, and blood sugar levels to elevate.

DMARDs (Disease Modifying Anti Rheumatic Drugs

This is another arthritis medication that targets arthritis as a disease and not just its symptoms. In this aspect, DMARDs are similar to BRMs, which also aims to halt progression of the disease. One key difference is that DMARDs, while effective, work slow and produce gradual results. Some types of this drug, like hydroxychloroquine for instance, may take three or four months before you notice any results. This gives you all the more reason to start it early.

This type of arthritis medication is commonly used for rheumatoid arthritis, as what its name suggests. However, there have been cases where this DMARDs were also used to treat juvenile rheumatoid arthritis, ankylosing spndylitis, psoriatic arthritis, and lupus.