Kidney Cancer

Kidney cancer occurs in approximately thirty one thousand Americans per year and most patients diagnosed are between the ages of fifty and seventy.  It affects men about twice as often as women.  At present, the causes of kidney cancer are not well understood and can seldom be explained why one person gets the disease and another doesn’t. Many factors are linked with the increased probability of kidney cancer; one major risk factor is cigarette smoking.  Smokers are twice likely to get the disease more than non-smokers.

Renal cell carcinoma, also known as gurnistical tumor, is the most common form of kidney cancer arising from the renal tubule, and the most common type of kidney cancer in adults.  The most common warning sign or symptom of this disease is blood in the urine.  In some cases, the person can actually see the blood.  It may be there one day and not the next.  A urine test done as a part of regular checkup called urinalysis may also find traces of blood in the urine. Another symptom is lump or mass that can be felt in the kidney area. The tumor may cause a dull ache or pain in the back side. Symptoms may develop abruptly. 

However, as with other cancer types, kidney cancer can cause a general feeling of poor health.  Weight loss, fever, feeling very tired, and loss of appetite can be some more symptoms felt by someone with the disease. Though most often, these symptoms do not mean cancer.  Other conditions may be causing the symptom that is why consulting a doctor is best advised when one experiences any of these problems.

To diagnose a kidney cancer, the patient’s personal and family medical history is taken and a thorough physical examination is conducted.  The doctor usually orders blood and urine tests and may do one or more of these exams:

IVP (Intravenous Pyelogram) is a test that lets the doctor see the kidneys, ureters, and bladder on x-rays. The x-rays are taken after an injection of dye that shows up on the x-ray film.

CT or CAT Scan is another x-ray procedure that gives detailed pictures of cross-sections of the body. The pictures are created by a computer.

Ultrasound is a test that sends high-frequency sound waves, which cannot be heard by humans, into the kidney. The pattern of echoes produced by these waves creates a picture called a sonogram. Healthy tissues, cysts, and tumors produce different echoes.

Arteriogram is a series of x-rays of blood vessels. Dye is injected into a large blood vessel through a narrow tube called a catheter. X-rays show the dye as it moves through the network of smaller blood vessels around and in the kidney.

MRI (Magnetic Resonance Imaging) uses a very strong magnet linked to a computer to create pictures of cross-sections of the kidney.

Nephrotomogram is a series of x-rays of cross-sections of the kidney. The x-rays are taken from several angles before and after injection of a dye that outlines the kidney.

When a person is diagnosed with kidney cancer, it is important to know the extent, or stage of the disease because it can spread to the bones, lungs, liver, and brain. Staging procedures may include special x-rays and tests to check these organs.

If the disease is only in the kidneys, which is about forty percent of cases, it can be cured roughly ninety percent of the time with surgery.  But if it has spread outside of the kidneys, often into the lymph nodes or the main vein of the kidney, then it must be treated with chemotherapy and other treatments.

Gouty Arthritis

Gouty arthritis or more commonly called gout is a form of arthritis that is characterized by sudden, severe attacks of pain, redness and tenderness in joints.  It is caused by deposits of needle-like crystals of uric acid, and is a complex disorder.  Luckily this disorder is treatable and there are ways of keeping it from recurring.

Cause of Gouty Arthritis
The cause of gout is an accumulation of urate crystals that results to inflammation of the joint.  Uric acid is a waste product of the body formed from the breakdown of purines which would normally be flushed out by the kidneys through urine.  But sometimes when the body either produces too much or excretes too little of this acid, uric acid can build up forming sharp, needle-like crystals (urate) in a joint or surrounding tissue that causes pain, inflammation and swelling.

These crystal deposits can also cause another condition known as false gout (pseudogout). But pseudogout crystals are made of calcium pyrophosphate dehydrate rather than of uric acid. Although pseudogout can affect the big toe, it’s more likely to attack large joints such as the knees, wrists and ankles.

Signs and Symptoms of Gouty Arthritis
The signs and symptoms of gouty arthritis occurs suddenly, often at night, without warning, however these symptoms are almost always acute.

Intense Joint Pain
Gouty arthritis generally affects the large joint of the big toe, but can also occur in your feet, ankles, knees, hands and wrists.  The pain usually lasts five to ten days and then stops, it subside gradually over one to two weeks leaving the joint actually normal and pain-free.

Inflammation and Redness
The joints that are affected become swollen, tender and red.

Four Stages of Gouty Arthritis
Gouty arthritis can be categorized into four stages but does not usually progress when proper treatment is given.

Asymptomatic Hyperuricemia
This stage doesn’t usually require treatment; in this stage the person has high levels of blood uric acid but no other symptoms.

Acute Gout / Acute Gouty Arthritis
In this stage of gouty arthritis, hyperuricemia has caused deposits of uric acid crystals in joint spaces, leading to gouty attacks.

Interval / Intercritical
This is the period between acute gouty arthritis attacks, a person has no symptoms.

Chronic Tophaceous Gout
This is the advance stage of gouty arthritis, where the disease has caused permanent damage.  However, most never progress to this stage with proper treatment.

Prevention of Gouty Arthritis
There is no exact and sure way of preventing gout.  If you already have gout, the doctor may prescribe certain drugs to reduce the risk or lessen the severity of future attacks.  Some of these drugs include allopurinol (Zyloprim, Aloprim) and probenecid. When taken daily, these drugs can slow the rate at which uric acid is produced and speed its elimination in the body.  Generally, the long-term key to preventing gouty arthritis is keeping uric acid levels within a normal range.